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Another great site is Cross-Pollinate, started by an American couple in Rome (my pal G and I stayed at their Roman hostel back in 2007). Just this past summer Chris and I booked a week long stay at a one bedroom apartment in Paris with the help of this site.
I'd gladly take the travel bug over the flu bug ANY day. Topping my list are Boston, London, and Amsterdam. Is there somewhere that you've been dreaming of going or an unforgettable place you've seen already? Please share!